Mentoring Vision Research in Oklahoma
COBRE
Department of Ophthalmology
University of Oklahoma Health Sciences Center
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John Ash, Ph.D.

Wei Cao, Ph.D.

Michael Ihnat, Ph.D.

Yun Le, Ph.D.

Raju Rajala, Ph.D.
PROMISING JUNIOR INVESTIGATOR
JOHN ASH, PH.D.


Dr. John Ash is a well-trained molecular biologist who did a postdoctoral fellowship with Dr. Paul Overbeek, a vision researcher at Baylor College of Medicine, where he studied the role of growth factors on the development and maintenance of retinal vasculature. In the Overbeek lab, he developed transgenic mice that express growth factors driven by the lens alpha-crystalline promoter. He submitted an R01 application, which was not funded primarily because the study section thought that the growth factors should be produced in the retina under the control of cell specific promoters such as the rod opsin promotor, rather than in the lens. With funding from the COBRE award, Dr. Ash will have the resources to develop his new transgenic models of retinal vascular development and gather enough preliminary data to make him competitive for R01 funding. Dr. Ash has received grant support from the Oklahoma Center for the Advancement of Science and Technology (OCAST), the Knights Templar Eye Foundation, the OUHSC alumni, and the Presbyterian Health Foundation (PHF).

COBRE Research Project

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